| Status | Available to order |
| EMMA ID | EM:06220 |
| Citation information | RRID:IMSR_EM:06220 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Atrtm2Ofc/Cnbc |
| Alternative name | Atr |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Atrtm2Ofc |
| Gene/Transgene symbol | Atr |
| Provider | Oskar Fernandez-Capetillo |
| Provider affiliation | Molecular Oncology, Centro Nacional de Investigaciones Oncologicas (CNIO) |
| Genetic information | Exons 8 through 10 were replaced with the corresponding wt human sequence including corresponding introns. |
| Phenotypic information | A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. PubMed ID: 19620979. |
| Breeding history | Chimeras were crossed with C57BL/6J females for germ line transmission testing. Currently maintained by crossing homozygous mice. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | homozygous C57BL/6J males |
Orphanet associated rare diseases, based on orthologous gene matching
