C57BL/6-Aca71/Ieg

Status	Available to order
EMMA ID	EM:07335
International strain name	C57BL/6-Aca71/Ieg
Alternative name	Aca71
Strain type	Induced Mutant Strains : Chemically-induced
Allele/Transgene symbol	Aca71,
Gene/Transgene symbol	Aca71

Information from provider

Provider	Jochen Graw
Provider affiliation	Institute of Developmental Genetics, Helmholtz Zentrum Muenchen
Genetic information	C57BL/6 background; the mutation is not identified. Linkage analysis failed because the phenotype was not identified in the F2 animals. The symbol Aca71 is used for this mutant line, because it was found with the AC-Master (device to determine the eye size); Aca = AC-Master abnormality (#71). Disclaimer - Special restrictions: 1) Mutant development was phenotype driven. Although for some mutant lines, linkage data and the molecular characterization of the causative mutation has been published, EMMA has not genotyped the strains and can not provide genotyping protocols. 2) Some lines showed low penetrance of the phenotype. 3) Only sperm available. Rederivation service can not be offered. 4) EMMA quality control standards may not apply for these strains. 5) EMMA has not verified the breeding performance and the genetic background of the strains. The genotype/phenotype of the mice is not confirmed by INFRAFRONTIER/EMMA. We strongly recommend that the recipient confirms genotype/phenotype upon receipt.
Phenotypic information	The Aca71 mutant was identified by Oliver Puk using the AC Master (Zeiss). The mutants are characterized by smaller lenses, which might lead to cataracts, when the mice become older.
Breeding history	brother x sister breeding
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	not known
Immunocompromised	not known

Information from EMMA

Archiving centre	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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