- decreased bone mineral density / IMPC
- preweaning lethality, complete penetrance / IMPC
- decreased bone mineral content / IMPC
- decreased lean body mass / IMPC
- increased total body fat amount / IMPC
- decreased red blood cell distribution width / IMPC
- increased circulating serum albumin level / IMPC
- decreased neutrophil cell number / IMPC
C57BL/6N-Flnbtm1a(KOMP)Wtsi/H
Status | Available to order |
EMMA ID | EM:07802 |
Citation information | RRID:IMSR_EM:07802 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6N-Flnbtm1a(KOMP)Wtsi/H |
Alternative name | EPD0585_1_F09 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Flnbtm1a(KOMP)Wtsi |
Gene/Transgene symbol | Flnb |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from KOMP ES clone EPD0585_1_F09. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Spondylocarpotarsal synostosis / Orphanet_3275
- Atelosteogenesis type I / Orphanet_1190
- Atelosteogenesis type III / Orphanet_56305
- Boomerang dysplasia / Orphanet_1263
- Larsen syndrome / Orphanet_503
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- delayed bone ossification / MGI
- decreased bone mineral density / MGI
- kyphoscoliosis / MGI
- abnormal neurocranium morphology / MGI
- abnormal parietal bone morphology / MGI
- decreased compact bone thickness / MGI
- rib fusion / MGI
- abnormal sternum morphology / MGI
- kyphosis / MGI
- scoliosis / MGI
- lordosis / MGI
- abnormal chondrocyte morphology / MGI
- abnormal angiogenesis / MGI
- short limbs / MGI
- abnormal radius morphology / MGI
- decreased body height / MGI
- decreased body weight / MGI
- decreased body size / MGI
- abnormal gait / MGI
- dehydration / MGI
- abnormal posture / MGI
- postnatal growth retardation / MGI
- abnormal motor capabilities/coordination/movement / MGI
- premature death / MGI
- abnormal skeleton development / MGI
- abnormal limb bone morphology / MGI
- brachyphalangia / MGI
- short tibia / MGI
- abnormal bone mineralization / MGI
- abnormal long bone epiphyseal plate morphology / MGI
- decreased rib number / MGI
- increased width of hypertrophic chondrocyte zone / MGI
- decreased width of hypertrophic chondrocyte zone / MGI
- abnormal artery development / MGI
- delayed endochondral bone ossification / MGI
- delayed intramembranous bone ossification / MGI
- abnormal cell adhesion / MGI
- abnormal long bone epiphyseal plate proliferative zone / MGI
- abnormal sternebra morphology / MGI
- short radius / MGI
- vertebral fusion / MGI
- cervical vertebral fusion / MGI
- thoracic vertebral fusion / MGI
- abnormal thoracic cage morphology / MGI
- thin ribs / MGI
- absent intervertebral disk / MGI
- decreased length of long bones / MGI
- abnormal vertebral column morphology / MGI
- abnormal brain vasculature morphology / MGI
- abnormal ulna morphology / MGI
- abnormal occipital bone morphology / MGI
- abnormal viscerocranium morphology / MGI
- abnormal patella morphology / MGI
- tachypnea / MGI
- abnormal cell physiology / MGI
- abnormal perichondrium morphology / MGI
- decreased long bone epiphyseal plate size / MGI
- abnormal hyaline cartilage morphology / MGI
- decreased diameter of radius / MGI
- decreased diameter of ulna / MGI
- abnormal bone ossification / MGI
- slow postnatal weight gain / MGI
- decreased survivor rate / MGI
- fused carpal bones / MGI
- abnormal chondrocyte physiology / MGI
- small thoracic cage / MGI
- postnatal lethality, incomplete penetrance / MGI
- neonatal lethality, incomplete penetrance / MGI
- perinatal lethality, incomplete penetrance / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- preweaning lethality, incomplete penetrance / MGI
- decreased fibroblast cell migration / MGI
- abnormal extracellular matrix morphology / MGI
- decreased bone ossification / MGI
- decreased bone mineralization / MGI
- abnormal middle cerebral artery morphology / MGI
- joint laxity / MGI
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