IMPC phenotypes (gene matching)
C57BL/6N-Chrnb2tm1a(EUCOMM)Hmgu/H
| Status | Available to order |
| EMMA ID | EM:07867 |
| Citation information | RRID:IMSR_EM:07867 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Chrnb2tm1a(EUCOMM)Hmgu/H |
| Alternative name | HEPD0739_7_H05 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Chrnb2tm1a(EUCOMM)Hmgu |
| Gene/Transgene symbol | Chrnb2 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from EUCOMM ES clone HEPD0739_7_H05. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal dominant nocturnal frontal lobe epilepsy / Orphanet_98784
MGI phenotypes (gene matching)
- abnormal superior colliculus morphology / MGI
- abnormal social investigation / MGI
- decreased anxiety-related response / MGI
- hyperactivity / MGI
- abnormal response to new environment / MGI
- abnormal immune system physiology / MGI
- apnea / MGI
- decreased chemically-elicited antinociception / MGI
- abnormal associative learning / MGI
- premature death / MGI
- abnormal brain morphology / MGI
- no abnormal phenotype detected / MGI
- abnormal nervous system electrophysiology / MGI
- abnormal tidal volume / MGI
- abnormal pulmonary ventilation / MGI
- decreased immunoglobulin level / MGI
- abnormal immunoglobulin level / MGI
- increased IgG level / MGI
- abnormal response to novelty / MGI
- enhanced coordination / MGI
- impaired passive avoidance behavior / MGI
- abnormal lateral geniculate nucleus morphology / MGI
- abnormal behavior / MGI
- decreased B cell number / MGI
- increased B cell proliferation / MGI
- decreased susceptibility to injury / MGI
- homeostasis/metabolism phenotype / MGI
- behavior/neurological phenotype / MGI
- immune system phenotype / MGI
- respiratory system phenotype / MGI
- vision/eye phenotype / MGI
- abnormal eye electrophysiology / MGI
- increased pulmonary ventilation / MGI
- increased tidal volume / MGI
- decreased visual acuity / MGI
- fragmentation of sleep/wake states / MGI
- abnormal nicotine-mediated receptor currents / MGI
- myeloid hyperplasia / MGI
- decreased erythroblast number / MGI
- abnormal habituation to a new environment / MGI
- enhanced spatial learning / MGI
- increased susceptibility to induction of seizure by inducing agent / MGI
- abnormal behavioral response to nicotine / MGI