IMPC phenotypes (gene matching)
C57BL/6N-Reltm1a(EUCOMM)Wtsi/H
| Status | Available to order |
| EMMA ID | EM:07990 |
| Citation information | RRID:IMSR_EM:07990 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Reltm1a(EUCOMM)Wtsi/H |
| Alternative name | EPD0463_4_D10 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Reltm1a(EUCOMM)Wtsi |
| Gene/Transgene symbol | Rel |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0463_4_D10. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- extramedullary hematopoiesis / MGI
- decreased bone marrow cell number / MGI
- abnormal stomach morphology / MGI
- abnormal liver morphology / MGI
- abnormal spleen morphology / MGI
- enlarged spleen / MGI
- enlarged lymph nodes / MGI
- abnormal lung morphology / MGI
- dermatitis / MGI
- impaired hematopoiesis / MGI
- abnormal humoral immune response / MGI
- decreased IgG level / MGI
- decreased IgM level / MGI
- premature death / MGI
- no abnormal phenotype detected / MGI
- abnormal dendritic cell physiology / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal leukocyte physiology / MGI
- abnormal T cell physiology / MGI
- abnormal macrophage morphology / MGI
- abnormal macrophage physiology / MGI
- abnormal professional antigen presenting cell physiology / MGI
- decreased IgE level / MGI
- increased IgM level / MGI
- increased IgA level / MGI
- abnormal cytokine secretion / MGI
- abnormal cell cycle / MGI
- increased neuron apoptosis / MGI
- impaired macrophage chemotaxis / MGI
- decreased susceptibility to experimental autoimmune encephalomyelitis / MGI
- decreased susceptibility to autoimmune diabetes / MGI
- decreased B-1 B cell number / MGI
- increased eosinophil cell number / MGI
- increased T cell number / MGI
- decreased susceptibility to parasitic infection / MGI
- decreased cytotoxic T cell cytolysis / MGI
- decreased B cell proliferation / MGI
- decreased T cell proliferation / MGI
- immune system phenotype / MGI
- respiratory system phenotype / MGI
- abnormal CD4-positive, alpha-beta T cell physiology / MGI
- abnormal skeleton morphology / MGI
- decreased apoptosis / MGI
- abnormal DNA replication / MGI
- increased CD4-positive, alpha beta T cell number / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- decreased CD8-positive, alpha-beta T cell number / MGI
- abnormal T-helper 1 cell differentiation / MGI
- abnormal memory B cell number / MGI
- abnormal spleen B cell follicle morphology / MGI
- decreased spleen germinal center number / MGI
- decreased IgG1 level / MGI
- decreased IgG2a level / MGI
- decreased IgG2b level / MGI
- decreased IgG3 level / MGI
- increased IgG2a level / MGI
- abnormal splenic cell ratio / MGI
- increased effector memory CD4-positive, alpha-beta T cell number / MGI
- decreased response to antigen / MGI