MGI phenotypes (gene matching)
B6.129P2-Mirc21tm1Doca/Cnrm
| Status | Available to order |
| EMMA ID | EM:08372 |
| Citation information | RRID:IMSR_EM:08372 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129P2-Mirc21tm1Doca/Cnrm |
| Alternative name | mir-34bc FLOX |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Mirc21tm1Doca |
| Gene/Transgene symbol | Mirc21 |
Information from provider
| Provider | Donal O'Carroll |
| Provider affiliation | Mouse Biology Unit, EMBL |
| Genetic information | Two loxP site surrounding the exons coding for the pri-Mir34b and pri-Mir34c in chromosome 9. |
| Phenotypic information | Homozygous:No phenotypeHeterozygous:No phenotype |
| Breeding history | Backcrossed to C57BL/6N, N=12 |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b/c and miR-449 loci.;Comazzetto Stefano, Di Giacomo Monica, Rasmussen Kasper Dindler, Much Christian, Azzi Chiara, Perlas Emerald, Morgan Marcos, O'Carroll Dónal, ;2014;PLoS genetics;10;e1004597; 25329700