MGI phenotypes (allele matching)
C57BL/6N-Atm1Brd Dusp5tm1a(KOMP)Wtsi/WtsiOrl
| Status | Available to order |
| EMMA ID | EM:08517 |
| Citation information | RRID:IMSR_EM:08517 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Atm1Brd Dusp5tm1a(KOMP)Wtsi/WtsiOrl |
| Alternative name | EPD0575_3_B05 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Dusp5tm1a(KOMP)Wtsi |
| Gene/Transgene symbol | Dusp5 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from KOMP ES clone EPD0575_3_B05. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6NTac males |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased thymocyte number / MGI
- abnormal bone marrow cell morphology/development / MGI
- abnormal T cell physiology / MGI
- increased incidence of tumors by chemical induction / MGI
- abnormal CD8-positive, alpha beta T cell morphology / MGI
- increased T cell proliferation / MGI
- immune system phenotype / MGI
- increased T cell apoptosis / MGI
- increased effector memory CD8-positive, alpha-beta T cell number / MGI
- altered susceptibility to parasitic infection / MGI