B6.Cg-Dicer1tm1.1Doca/Cnrm
| Status | Available to order |
| EMMA ID | EM:08527 |
| International strain name | B6.Cg-Dicer1tm1.1Doca/Cnrm |
| Alternative name | FH-Dicer |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Dicer1tm1.1Doca, |
| Gene/Transgene symbol | Dicer1 |
Information from provider
| Provider | Donal O'Carroll |
| Provider affiliation | EMBL Monterotondo |
| Genetic information | Knock-in strain expressing a N-terminally FLAG-HA2 epitope-tagged Dicer. |
| Phenotypic information | Homozygous:No phenotype observed.Heterozygous:No phenotype observed. |
| Breeding history | The mice were generated by targeting ES cells of A9/129/Sv background and by backcrossing heterozygotes to B6N mice (8 generations at the moment). |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Global developmental delay-lung cysts-overgrowth-Wilms tumor syndrome / Orphanet_404476
- Pleuropulmonary blastoma familial tumor susceptibility syndrome / Orphanet_284343
- Embryonal rhabdomyosarcoma / Orphanet_99757