C57BL/6N-Atm1Brd Atf2tm1a(EUCOMM)Hmgu/Ph
| Status | Available to order |
| EMMA ID | EM:09148 |
| International strain name | C57BL/6N-Atm1Brd Atf2tm1a(EUCOMM)Hmgu/Ph |
| Alternative name | B6.Atf2tm1a |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Atf2tm1a(EUCOMM)Hmgu, |
| Gene/Transgene symbol | Atf2 |
Information from provider
| Provider | Regine Schneider-Stock |
| Provider affiliation | Pathologisches Institut , Universitätsklinikum Erlangen |
| Genetic information | Atf2 gene was conditionally targeted by insertion of a reporter-tagged cassette containing lacZ, neomycin resistance, Frt and LoxP sequences. Exons 6-7 were targeted by homologous recombination and electroporation of the targeting construct into C57BL/6N-A/a ES cells. The targeting resulted in a so called "knockout-first allele". LacZ and neomycin cassettes together are flanked by Frt sites; neomycin cassette and targeted exons 6-7 are flanked by LoxP sites. Positive targeted ES cell clones were injected into C57BL/6N embryos. |
| Phenotypic information | Homozygous:The strain was not bred for homozygous mice. Phenotype unknown.Heterozygous:Heterozygous mice appear normal like wild-type animals. No obvious phenotype. |
| Breeding history | Chimeric mice were paired with wild-type C57BL/6N partners to test for germ-line transmission and to obtain heterozygous F1 generation mice. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | heterozygous C57BL/6NCrl |