MGI phenotypes (allele matching)
STOCK Samd8tm1.1Kwi/Cnrm
| Status | Available to order |
| EMMA ID | EM:09172 |
| International strain name | STOCK Samd8tm1.1Kwi/Cnrm |
| Alternative name | B6N;129P2-SMSrtm10Kwi/Cnrm |
| Strain type | Targeted Mutant Strains : Point mutation |
| Allele/Transgene symbol | Samd8tm1.1Kwi, |
| Gene/Transgene symbol | Samd8 |
Information from provider
| Provider | Klaus Willecke |
| Provider affiliation | Molecular Genetics, Limes Institute |
| Genetic information | Smsr (Samd8) D348E |
| Phenotypic information | Homozygous:Fertile with no obvious phenotypic abnormalitiesHeterozygous:Fertile with no obvious phenotypic abnormalities |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis.;Tafesse Fikadu G, Vacaru Ana M, Bosma Elleke F, Hermansson Martin, Jain Amrita, Hilderink Angelika, Somerharju Pentti, Holthuis Joost C M, ;2014;Journal of cell science;127;445-54; 24259670
- Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER.;Vacaru Ana M, Tafesse Fikadu G, Ternes Philipp, Kondylis Vangelis, Hermansson Martin, Brouwers Jos F H M, Somerharju Pentti, Rabouille Catherine, Holthuis Joost C M, ;2009;The Journal of cell biology;185;1013-27; 19506037