C57BL/6N-Gltptm1a(EUCOMM)Hmgu/Ph
| Status | Available to order |
| EMMA ID | EM:09379 |
| International strain name | C57BL/6N-Gltptm1a(EUCOMM)Hmgu/Ph |
| Alternative name | B6.Gltptm1a |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Gltptm1a(EUCOMM)Hmgu, |
| Gene/Transgene symbol | Gltp |
Information from provider
| Provider | Dagmar Wachten |
| Provider affiliation | Molecular Physiology, caesar - center of advanced european studies and research of the Max Planck Society |
| Genetic information | Gltp gene was conditionally targeted by insertion of a reporter-tagged cassette containing lacZ, neomycin resistance, Frt and LoxP sequences. Exon 2 was targeted by homologous recombination and electroporation of the targeting construct into C57BL/6N ES cells. The targeting resulted in a so called "knockout-first allele". LacZ and neomycin cassettes together are flanked by Frt sites; neomycin cassette and targeted exon2 are flanked by LoxP sites. |
| Phenotypic information | Homozygous:Not known, until now mice were bred on heterozygous basis only.Heterozygous:Heterozygous mice show no obvious phenotype and appear normal. |
| Breeding history | Chimeric founder mice were generated by injection of C57BL/6N ES cells into C57BL/6J albino (B6(Cg)-Tyrc-2J/J) embryos. Chimeras were bred to C57BL/6N partner to test for germ-line transmission. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |