C57BL/6N-Gltptm1a(EUCOMM)Hmgu/Ph
| Status | Available to order |
| EMMA ID | EM:09379 |
| Citation information | RRID:IMSR_EM:09379 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Gltptm1a(EUCOMM)Hmgu/Ph |
| Alternative name | B6.Gltptm1a |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Gltptm1a(EUCOMM)Hmgu |
| Gene/Transgene symbol | Gltp |
Information from provider
| Provider | Dagmar Wachten |
| Provider affiliation | Molecular Physiology, caesar - center of advanced european studies and research of the Max Planck Society |
| Genetic information | Gltp gene was conditionally targeted by insertion of a reporter-tagged cassette containing lacZ, neomycin resistance, Frt and LoxP sequences. Exon 2 was targeted by homologous recombination and electroporation of the targeting construct into C57BL/6N ES cells. The targeting resulted in a so called "knockout-first allele". LacZ and neomycin cassettes together are flanked by Frt sites; neomycin cassette and targeted exon2 are flanked by LoxP sites. |
| Phenotypic information | Homozygous:Not known, until now mice were bred on heterozygous basis only.Heterozygous:Heterozygous mice show no obvious phenotype and appear normal. |
| Breeding history | Chimeric founder mice were generated by injection of C57BL/6N ES cells into C57BL/6J albino (B6(Cg)-Tyrc-2J/J) embryos. Chimeras were bred to C57BL/6N partner to test for germ-line transmission. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |