B6N.Cg-Tg(Egr1-luc)5Ddl/Biat
| Status | Available to order |
| EMMA ID | EM:09753 |
| Citation information | RRID:IMSR_EM:09753 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6N.Cg-Tg(Egr1-luc)5Ddl/Biat |
| Alternative name | B6N.Cg-Tg(Egr1-Luc)5Bnh/MMCT |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Egr1-Luc)5Bnh |
| Gene/Transgene symbol | Tg(Egr1-Luc)5Bnh |
Information from provider
| Provider | Elisabeth Deindl |
| Provider affiliation | Walter-Brendel-Center for Experimental Medicine , Ludwig-Maximilians-University |
| Additional owner | Submitted to EMMA by Prof. Manfred Ogris, University of Vienna, Vienna, Austria and Dr. Elisabeth Deindl, Ludwig-Maximilians-University, Munich, Germany |
| Genetic information | The firefly luciferase reporter gene is expressed under the control of the murine Early-growth-response-1 promoter (Egr1). |
| Phenotypic information | Homozygous:Firefly luciferase expression under the control of the murine Egr1 promoter (as active enzyme and on mRNA level) in embryonic, neonatal and regenerating tissue.Heterozygous:Firefly luciferase expression under the control of the murine Egr1 promoter (as active enzyme and on mRNA level) in embryonic, neonatal and regenerating tissue. |
| Breeding history | Animals were initially generated by microinjection of the Egr1-Luc reporter cassette into the male pronuclei of C57BL/6 and propagated for more than 6 generations in this strain. Thereafter animals were backcrossed into C57BL/6 albino mice obtained from Charles River (B6N-Tyrc-Brd/BrdCrCrl) and maintained for more than 6 generations. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | heterozygous Other (please specify below) males |
Literature references
- Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing.;Dussmann Philipp, Pagel Judith I, Vogel Sabina, Magnusson Terese, Zimmermann Rene, Wagner Ernst, Schaper Wolfgang, Ogris Manfred, Deindl Elisabeth, ;2011;BMC developmental biology;11;28; 21595990