FVB-Tg(MMTV-PRUNE1)1Nmrn/Cnrm
| Status | Available to order |
| EMMA ID | EM:09937 |
| Citation information | RRID:IMSR_EM:09937 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB-Tg(MMTV-PRUNE1)1Nmrn/Cnrm |
| Alternative name | MMTV-Prune |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(MMTV-PRUNE1)1Nmrn |
| Gene/Transgene symbol | Tg(MMTV-PRUNE1)1Nmrn |
Information from provider
| Provider | Massimo Zollo |
| Provider affiliation | MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE, FEDERICO II |
| Genetic information | Transgenic mice. MMTV promoter-driven expression of H-PRUNE full-length cDNA in the mammary gland. |
| Phenotypic information | Homozygous:Breast cancer.Heterozygous:No phenotype. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Prune-1 drives polarization of tumor-associated macrophages (TAMs) within the lung metastatic niche in triple-negative breast cancer.;Ferrucci Veronica, Asadzadeh Fatemeh, Collina Francesca, Siciliano Roberto, Boccia Angelo, Marrone Laura, Spano Daniela, Carotenuto Marianeve, Chiarolla Cristina Maria, De Martino Daniela, De Vita Gennaro, Macrì Alessandra, Dassi Luisa, Vandenbussche Jonathan, Marino Natascia, Cantile Monica, Paolella Giovanni, D'Andrea Francesco, di Bonito Maurizio, Gevaert Kris, Zollo Massimo, ;2021;iScience;24;101938; 33426510