IMPC phenotypes (allele matching)
C57BL/6-Setdb2tm1a(KOMP)Wtsi/Biat
| Status | Available to order |
| EMMA ID | EM:11046 |
| International strain name | C57BL/6-Setdb2tm1a(KOMP)Wtsi/Biat |
| Alternative name | Setdb2 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Setdb2tm1a(KOMP)Wtsi |
| Gene/Transgene symbol | Setdb2 |
Information from provider
| Provider | David Symer |
| Provider affiliation | Dept. of Lymphoma & Myeloma, Univ. Texas MD Anderson Cancer Center |
| Genetic information | A gene-trap construct together with loxP sites were introduced up- and downstream of exon 6 of Setdb2. The knockout first allele is initially a non-expressive form, but can be converted to a conditional allele via flp recombinase-mediated recombination. |
| Phenotypic information | Homozygous:altered immune responseHeterozygous:not performed |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | yes |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | homozygous C57BL/6 |