CBA/J-Chr 17NOD/GhjCnrm
| Status | Available to order |
| EMMA ID | EM:01406 |
| International strain name | CBA/J-Chr 17NOD/GhjCnrm |
| Alternative name | CBA.NOD-C17S |
| Strain type | Spontaneous |
| Allele/Transgene symbol | Chr 17NOD |
| Gene/Transgene symbol | Chr 17 |
Information from provider
| Provider | Henri-Jean Garchon |
| Provider affiliation | ER70 CNRS et Unite 125 Inserm |
| Genetic information | CBA/J consomic strain with the Chr17 substituted from the non-obese diabetic (NOD) strain. |
| Phenotypic information | This line and the related lines, consomic, congenic and subcongenic for chromosome 17 and fragments of this chromosome, were derived to thoroughly investigate the role of the major histocompatibility complex (MHC) and MHC-linked genes in autoimmune predisposition, notably including type I diabetes (Idd1 and Idd16) loci and chronic autoimmune thyroiditis (Ceat1) locus, on the CBA/J background. |
| Breeding history | 6 generations of backcrosses selected with the speed congenic approach, followed by sister-brother matings. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- An interval tightly linked to but distinct from the H2 complex controls both overt diabetes (Idd16) and chronic experimental autoimmune thyroiditis (Ceat1) in nonobese diabetic mice.;Boulard Olivier, Damotte Diane, Deruytter Nathalie, Fluteau Guy, Carnaud Claude, Garchon Henri-Jean, ;2002;Diabetes;51;2141-7; 12086944
- Mapping non-class II H2-linked loci for type 1 diabetes in nonobese diabetic mice.;Deruytter Nathalie, Boulard Olivier, Garchon Henri-Jean, ;2004;Diabetes;53;3323-7; 15561967