MGI phenotypes (allele matching)
B10.BR-H2k/SnOrl
| Status | Available to order |
| EMMA ID | EM:00034 |
| International strain name | B10.BR-H2k/SnOrl |
| Alternative name | C57BL/10BR |
| Strain type | Other |
| Allele/Transgene symbol | H2k |
| Gene/Transgene symbol | H2 |
Information from provider
| Provider | CDTA unknown |
| Provider affiliation | CNRS-Orleans |
| Phenotypic information | Sub-strain of C57BL/10, congenic for H2-K haplotype. Genetic background of C57BL/10 with introduction of a different allele (H2-K) derived from C57BR/Orl strain |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased hematocrit / MGI
- abnormal liver physiology / MGI
- abnormal T cell differentiation / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal immunoglobulin level / MGI
- increased IgM level / MGI
- abnormal cytokine secretion / MGI
- thyroid inflammation / MGI
- increased autoantibody level / MGI
- insulitis / MGI
- increased susceptibility to autoimmune diabetes / MGI
- decreased susceptibility to autoimmune diabetes / MGI
- decreased susceptibility to parasitic infection / MGI
- immune system phenotype / MGI
- periinsulitis / MGI
- abnormal T cell number / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- decreased IgG1 level / MGI
- decreased IgG2a level / MGI
- increased physiological sensitivity to xenobiotic / MGI
- decreased physiological sensitivity to xenobiotic / MGI
- increased sensitivity to induced morbidity/mortality / MGI
Literature references
- Induction of resistance to antibody-mediated cytotoxicity. H-2, Ia, and Ig antigens are independent entities in the membrane of mouse lymphocytes.;Hauptfeld V, Hauptfeld M, Klein J, ;1975;The Journal of experimental medicine;141;1047-56; 47892