B6.129-Siglec1tm1Croc/CrocH
| Status | Available to order |
| EMMA ID | EM:12765 |
| International strain name | B6.129-Siglec1tm1Croc/CrocH |
| Alternative name | Siglec-1 (CD169) KO mouse |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Siglec1tm1Croc, |
| Gene/Transgene symbol | Siglec1 |
Information from provider
| Provider | Paul Crocker |
| Provider affiliation | School of Life Sciences |
| Genetic information | Mouse knock-out model for the Siglec1/CD169 gene. |
| Phenotypic information | Homozygous:No overt phenotype.Heterozygous:No overt phenotype. |
| Breeding history | Backcrossed onto C57BL/6J for at least 8 generations. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Sialoadhesin-deficient mice exhibit subtle changes in B- and T-cell populations and reduced immunoglobulin M levels.;Oetke Cornelia, Vinson Mary C, Jones Claire, Crocker Paul R, ;2006;Molecular and cellular biology;26;1549-57; 16449664