- no phenotypic analysis / MGI
B6.129P2-Parltm1Bdes/Ieg
Status | Available to order |
EMMA ID | EM:02076 |
International strain name | B6.129P2-Parltm1Bdes/Ieg |
Alternative name | Parl conditional KO |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Parltm1Bdes, |
Gene/Transgene symbol | Parl |
Information from provider
Provider | Bart De Stropper |
Provider affiliation | Flanders interuniversitary institute for biotechnologies (VIB) |
Genetic information | LoxP sequences were inserted into intron 2 and intron 3 of Parl gene thus generating the Parl conditional allele Parltm1Bdes. |
Phenotypic information | None. |
Breeding history | The colony has been backcrossed 8 times to C57BL/6. |
References |
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Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
MGI phenotypes (allele matching)
Literature references
- Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.;Cipolat Sara, Rudka Tomasz, Hartmann Dieter, Costa Veronica, Serneels Lutgarde, Craessaerts Katleen, Metzger Kristine, Frezza Christian, Annaert Wim, D'Adamio Luciano, Derks Carmen, Dejaegere Tim, Pellegrini Luca, D'Hooge Rudi, Scorrano Luca, De Strooper Bart, ;2006;Cell;126;163-75; 16839884
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