MGI phenotypes (allele matching)
STOCK Bmp7tm2Rob/H
| Status | Available to order |
| EMMA ID | EM:02513 |
| International strain name | STOCK Bmp7tm2Rob/H |
| Alternative name | Bmp7 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Bmp7tm2Rob, |
| Gene/Transgene symbol | Bmp7 |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Genetic information | Knock-in allele at exon 1 of Bmp7 locus of an in-frame LacZ cassette. Expression of LacZ mimics endogenous activity of Bmp7 locus. LacZ cassette replaces endogenous BMP7 coding sequence to generate a null allele. |
| Phenotypic information | Homozygous embryonic lethal during late gestation. |
| Breeding history | Outcrossed onto a mixed background. Currently maintained by crossing to CD1. |
| References |
|
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- Regulation of BMP7 expression during kidney development.;Godin R E, Takaesu N T, Robertson E J, Dudley A T, ;1998;Development (Cambridge, England);125;3473-82; 9693150