New INFRAFRONTIER Article Published in Journal Mammalian Genome

At INFRAFRONTIER we accepted with great enthusiasm the invitation to submit a manuscript for the special issue “Mammalian Genetic Resources 2023” of the journal Mammalian Genome. After some months of dedication, we have made it! With this publication, “INFRAFRONTIER: mouse model resources for modelling human diseases”, we have made a comprehensive review of all the services, resources and innovative technologies that INFRAFRONTIER offers to the scientific community to advance the understanding and treatment of human diseases.

Abstract:
Over the last decade, INFRAFRONTIER has positioned itself as a world-class Research Infrastructure for the generation, phenotyping, archiving, and distribution of mouse models in Europe. The INFRAFRONTIER network consists of 22 partners from 15 countries, and is continuously enhancing and broadening its portfolio of resources and services that are offered to the research community on a non-profit basis. By bringing together European rodent model expertise and providing valuable disease model services to the biomedical research community, INFRAFRONTIER strives to push the accessibility of cutting-edge human disease modelling technologies across the European research landscape. This article highlights the latest INFRAFRONTIER developments and informs the research community about its extensively utilised services, resources, and technical developments, specifically the intricacies of the INFRAFRONTIER database, use of Curated Disease Models, overview of the INFRAFRONTIER Cancer and Rare Disease resources, and information about its main state-of-the-art services.

Original publication:
Ali Khan A, Valera Vazquez G, Gustems M, Matteoni R, Song F, Gormanns P, Fessele S, Raess M, Hrabĕ de Angelis M; INFRAFRONTIER Consortium. INFRAFRONTIER: mouse model resources for modelling human diseases. Mamm Genome. 2023 Jul 19. doi: 10.1007/s00335-023-10010-7 . Epub ahead of print. PMID: 37468728.

The INFRAFRONTIER Consortium is composed of these institutions:

• Biomedcode Hellas SA
• Biomedical Research Centre Alexander Fleming
• Centro Nacional de Biotecnologia (CNB-CSIC)
• Consiglio Nazionale delle Ricerche (CNR)
• Czech Centre for Phenogenomics (CCP)
• European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
• Helmholtz Zentrum München GmbH (HM)
• INFRAFRONTIER GmbH
• Instituto Gulbenkian de Ciência (IGC)
• Karolinska Institutet (KI)
• Mary Lion Centre at MRC Harwell
• Netherlands Cancer Institute (NKI)
• PHENOMIN CIPHE d’Immunophénomique
• PHENOMIN Institut Clinique de la Souris (ICS)
• PHENOMIN TAAM
• Tel Aviv University (TAU)
• Toronto Centre for Phenogenomics (TCP)
• Universitat Autonoma de Barcelona (UAB)
• University of Copenhagen (UCPH)
• University of Oulu
• Veterinärmedizinische Universität Wien (UniVetMed)