Institutions and facilities
The Germ-Free Oeiras Service (GFOS), providing the EMMA axenic service
The GFOS is part of the core animal facility of the Instituto Gulbenkian de Ciência in Oeiras, Portugal. The IGC mouse facility is partitioned into 5 independent areas, each with a specific bio-containment level, including germ-free and strict SPF. The facility hosts about 50,000 mice that cover close to a 100 different inbred strains, available to in-house and associated research groups and visiting scientists. Production and experimental areas are designed to serve active research in various fields of biology (development, neurobiology, infectious diseases, immunology, genetics). Ongoing scientific projects at the IGC involving the GFOS are related to studies of immuno-compromised mice.
The GFOS is adapted for breeding and experimentation purposes. Rigid and flexible Isolators, transfer chambers and containers are equipped with the Double Door Rapid Transfer Port (DPTE®), a user-friendly and safe connecting system for introducing and removing equipment and other materials to and from sterile isolators. Like other research facilities at the IGC, the GFOS is available to scientists worldwide upon agreement from the Institute's Director. Moreover, scientists who want to work with these mice can be temporarily hosted at the Institute's laboratories if they wish to conduct their own experiments.
Other academic and non-profit institutions where gnotobiology research is conducted in Europe
Transgenesis, Archiving and Animal Models (TAAM), CNRS, Orléans, France
Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
Core Facility for Germ Free Research (CFGR), Karolinska Institutet, Stockholm, Sweden
Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal
MRC Harwell, Harwell, UK
Additional institutions and other useful links are listed by the Association for Gnotobiotics.