FVB-Tg(CAG-cat,-lacZ)1Brn/StmOrl
| Status | Available to order |
| EMMA ID | EM:00005 |
| International strain name | FVB-Tg(CAG-cat,-lacZ)1Brn/StmOrl |
| Alternative name | ACZL |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CAG-cat, -lacZ)1Brn |
| Gene/Transgene symbol | Tg(CAG-cat,-lacZ)1Brn |
Information from provider
| Provider | Kiwamu AKAGI |
| Provider affiliation | Saitama Cancer Center Research Institute |
| Genetic information | Floxed-LacZ reporter mice were generated to assess the efficiency of cre recombinase-mediated site-specific recombination in vivo. |
| Phenotypic information | Floxed-LacZ reporter mice carry the chicken beta-actin promoter and beta-galactosidase (lacZ) transcription unit, separated by the chloramphenicol acetyltransferase (cat) gene, flanked by two loxP sites (floxed); the cat transcription unit prevents lacZ expression. The lacZ expression permits to monitor the activity of cre recombinase in vivo. |
| Breeding history | Heterozygous on FVB background. |
| References |
|
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Literature references
- Cre-mediated somatic site-specific recombination in mice.;Akagi K, Sandig V, Vooijs M, Van der Valk M, Giovannini M, Strauss M, Berns A, ;1997;Nucleic acids research;25;1766-73; 9108159