MGI phenotypes (allele matching)
STOCK Mut1488/H
| Status | Available to order |
| EMMA ID | EM:01977 |
| International strain name | STOCK Mut1488/H |
| Alternative name | MUT/1488 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Mut1488, |
| Gene/Transgene symbol | Mut1488 |
Information from provider
| Provider | Bruce Cattanach |
| Provider affiliation | MRC Harwell, Didcot, Oxon, OX11 0RD |
| Phenotypic information | Heterozygotes are less than 75% of the weight of their wild-type sibs at birth; limited weight data at weaning suggest that there is a similar size difference at this time point. Mut1488/+ have small eyes, occasionally with domed heads, some have white toes. Breeding data indicate that there is reduced penetrance of the mutation (circa 50%) on a 3H1 background. Data from openings indicate that homozygotes are lost soon after implantation. |
| Breeding history | Original background: (C3H/HeH x 101/H) x PT. Maintained background: C3H/HeH x 101/H. Breeding History: Backcrossed to C3H/HeH x 101/H. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191