STOCK Tg(Myh6-tTA)6Smbf/Cnrm
| Status | Available to order |
| EMMA ID | EM:04365 |
| International strain name | STOCK Tg(Myh6-tTA)6Smbf/Cnrm |
| Alternative name | alphaMHC-tTA |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Myh6-tTA)6Smbf, |
| Gene/Transgene symbol | Tg(Myh6-tTA)6Smbf |
Information from provider
| Provider | Glenn Fishman |
| Provider affiliation | NYU Langone Medical Center |
| Genetic information | Alpha-MHC-tTA mice contain the cardiac specific alpha-myosin heavy chain promoter driving the tetracycline transactivator (tTA). The murine line expresses tTA transactivator specifically in cardiomyocytes. This allows inducible expression of TetO responder gene in the heart with the tet-off system. |
| Phenotypic information | No phenotype defect detected. |
| Breeding history | They have been backcrossed to FVB. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
| Animals used for archiving | heterozygous FVB, wild-type FVB/N |
| Stage of embryos | 2-cell |
Literature references
- Conditional transgene expression in the heart.;Yu Z, Redfern C S, Fishman G I, ;1996;Circulation research;79;691-7; 8831492