MGI phenotypes (allele matching)
STOCK Gjd4tm1.1Malt/Cnrm
| Status | Available to order |
| EMMA ID | EM:05216 |
| International strain name | STOCK Gjd4tm1.1Malt/Cnrm |
| Alternative name | Cx39KO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Gjd4tm1.1Malt, |
| Gene/Transgene symbol | Gjd4 |
Information from provider
| Provider | Klaus WILLECKE |
| Provider affiliation | Molekulargenetik, Institut fuer Genetik, Universitaet Bonn |
| Genetic information | The Cx39 (Gjd4) deficient mice were generated by replacing the coding region of the Gjd4 gene with DNA coding for the enhanced green fluorescent protein eGFP. |
| Phenotypic information | No obvious phenotype but connexin 39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle. |
| Breeding history | Founder animals were backcrossed to C57BL/6 more than three times (more than 85%). |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle.;von Maltzahn Julia, Wulf Volker, Matern Gabi, Willecke Klaus, ;2011;Experimental cell research;317;1169-78; 21272575