C57BL/6N-Tlr7tm1.1Arte/Ieg
Status | Available to order |
EMMA ID | EM:05500 |
International strain name | C57BL/6N-Tlr7tm1.1Arte/Ieg |
Alternative name | Tlr7 KO cond |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Tlr7tm1.1 |
Gene/Transgene symbol | Tlr7 |
Information from provider
Provider | Helmholtz Zentrum Muenchen |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen German Research Center for Environmental Health (GmbH) |
Genetic information | Exon 3 has been flanked by loxP sites, as its genetic ablation should result in loss of function by deletion of most of the open reading frame. The conditional targeted mutation has been obtained by in vivo, Flp recombinase-mediated removal of the neomycin and puromycin selection markers. |
Phenotypic information | TO BE PROVIDED |
Breeding history | Targeting performed in C57BL/6N ES cells and confirmed by Southern blotting. Crossed to C57BL/6N-Tg(CAG-flpe)2Arte mice to obtain mutant founders with excised neo and puro cassettes. Maintained on C57BL/6N background. |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | homozygous C57BL/6NTac, wild-type C57BL/6N |
Stage of embryos | 2-cell |
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