B6.129S2-Tpm3Gt(A062D07)Wrst/Ieg
Status | Available to order |
EMMA ID | EM:05685 |
International strain name | B6.129S2-Tpm3Gt(A062D07)Wrst/Ieg |
Alternative name | Tpm3 (tropomyosin 3, gamma) |
Strain type | Gene-trap |
Allele/Transgene symbol | Tpm3Gt(A062D07)Wrst, |
Gene/Transgene symbol | Tpm3 |
Information from provider
Provider | Franz Vauti |
Provider affiliation | Cell- & Molecular Biology, Technical University of Braunschweig |
Genetic information | Tpm3 PT1betageo gene-trap. |
Phenotypic information | Not known; mouse line not yet characterized. |
Breeding history | Backcrossed into C57BL/6 (N>7). |
References |
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Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6J |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Congenital generalized hypercontractile muscle stiffness syndrome / Orphanet_476406
- Intermediate nemaline myopathy / Orphanet_171433
- Cap myopathy / Orphanet_171881
- Congenital fiber-type disproportion myopathy / Orphanet_2020
- Childhood-onset nemaline myopathy / Orphanet_171439
Literature references
- A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.;Hansen Jens, Floss Thomas, Van Sloun Petra, Füchtbauer Ernst-Martin, Vauti Franz, Arnold Hans-Hennig, Schnütgen Frank, Wurst Wolfgang, von Melchner Harald, Ruiz Patricia, ;2003;Proceedings of the National Academy of Sciences of the United States of America;100;9918-22; 12904583
- Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.;Wiles M V, Vauti F, Otte J, Füchtbauer E M, Ruiz P, Füchtbauer A, Arnold H H, Lehrach H, Metz T, von Melchner H, Wurst W, ;2000;Nature genetics;24;13-4; 10615117
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