C57BL/6N-Atm1Brd Kdm6atm2c(EUCOMM)Wtsi/WtsiH
Status | Available to order |
EMMA ID | EM:11128 |
International strain name | C57BL/6N-Atm1Brd Kdm6atm2c(EUCOMM)Wtsi/WtsiH |
Alternative name | EPD0506_3_A01 |
Strain type | Targeted Mutant Strains : Targeted Conditional |
Allele/Transgene symbol | Kdm6atm2c(EUCOMM)Wtsi |
Gene/Transgene symbol | Kdm6a |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This line originates from EUCOMM ES clone EPD0506_3_A01, after breeding with a Flp recombinase deleter line to convert the original targeted allele tm2a (knock-out first allele) into a conditional allele tm2c. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
Breeding history | The Kdm6a gene is on the X-chromosome. Hemizygous males are fertile |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | heterozygous C57BL/6NTacUSA |
Breeding at archiving centre | This is a hemizygous mutation on a C57BL/6NTac background |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Kabuki syndrome / Orphanet_2322
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