B6.Cg-Tg(IL3,CSF2)C42Pnc/H

Status	Available to order
EMMA ID	EM:09411
International strain name	B6.Cg-Tg(IL3,CSF2)C42Pnc/H
Alternative name	C42
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(IL3, CSF2)C42Pnc
Gene/Transgene symbol	Tg(IL3,CSF2)C42Pnc

Information from provider

Provider	Peter Cockerill
Provider affiliation	Biomedical Services Unit, University of Birmingham
Genetic information	Contains 6 copies of a 130kb fragment of the human IL-3/GM-CSF locus.
Phenotypic information	Normal.
Breeding history	Backcrossed 11 generations. Mice are now homozygous.
References	The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development.;Mirabella Fabio, Baxter Euan W, Boissinot Marjorie, James Sally R, Cockerill Peter N, ;2010;Journal of immunology (Baltimore, Md. : 1950);184;3043-54; 20147630
Homozygous fertile	yes
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Literature references

The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development.;Mirabella Fabio, Baxter Euan W, Boissinot Marjorie, James Sally R, Cockerill Peter N, ;2010;Journal of immunology (Baltimore, Md. : 1950);184;3043-54; 20147630

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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