STOCK Gt(ROSA)26Sortm1Hjf Tg(Siglech-cre,-mCherry)#Spar/Ph
| Status | Available to order |
| EMMA ID | EM:10455 |
| International strain name | STOCK Gt(ROSA)26Sortm1Hjf Tg(Siglech-cre,-mCherry)#Spar/Ph |
| Alternative name | C57Bl/6-Tg(SiglecH-cre)C2 Spar x Gt(ROSA)26SortmHJf |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Gt(ROSA)26Sortm1Hjf, |
| Gene/Transgene symbol | Gt(ROSA)26Sor |
Information from provider
| Provider | Tim Sparwasser |
| Provider affiliation | Institute for Infection Immunology, Twincore |
| Genetic information | The mouse promoter from BAC RP24-396N13 drives expression of a cre recombinase, IRES and mCherry construct in plasmacytoid dendritic cells. |
| Phenotypic information | Homozygous:noneHeterozygous:none |
| Breeding history | New breedings are always set up with plain Gt(ROSA)26Sortm1Hjf mice. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | heterozygous C57BL/6J |
| Breeding at archiving centre | New breedings are always set up with plain Gt(ROSA)26Sortm1Hjf. |
Literature references
- Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance.;Puttur Franz, Arnold-Schrauf Catharina, Lahl Katharina, Solmaz Gulhas, Lindenberg Marc, Mayer Christian Thomas, Gohmert Melanie, Swallow Maxine, van Helt Christopher, Schmitt Heike, Nitschke Lars, Lambrecht Bart N, Lang Roland, Messerle Martin, Sparwasser Tim, ;2013;PLoS pathogens;9;e1003648; 24086137