B6.Cg-Tg(Camk2a-cre)93Kln/KlnCnrm

Status	Available to order
EMMA ID	EM:01137
International strain name	B6.Cg-Tg(Camk2a-cre)93Kln/KlnCnrm
Alternative name	AlphaCaMKII-Cre
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Camk2a-cre)93Kln
Gene/Transgene symbol	Tg(Camk2a-cre)93Kln

Information from provider

Provider	Klaus Rajewsky
Provider affiliation	CBR Institute for Biomedical Research, Immune Disease Institute
Genetic information	The CamK-cre93 transgene directs the expression of cre recombinase under the control of the calcium/calmodulin-dependent protein kinase II promoter. The promoter is active starting at P21 in the cortex, hippocampus, hypothalamus and brainstem, but not in glia.
Phenotypic information	The strain is used for in vivo cre-mediated recombination, under the control of the calcium/calmodulin-dependent protein kinase II promoter. The promoter is active starting at P21 in the cortex, hippocampus, hypothalamus and brainstem, but not in glia.
Breeding history	Mixed 129 x CBA background, backcrossed to C57BL/6 (5-6 generations).
References	Essential role for TrkB receptors in hippocampus-mediated learning.;Minichiello L, Korte M, Wolfer D, Kühn R, Unsicker K, Cestari V, Rossi-Arnaud C, Lipp H P, Bonhoeffer T, Klein R, ;1999;Neuron;24;401-14; 10571233

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

Essential role for TrkB receptors in hippocampus-mediated learning.;Minichiello L, Korte M, Wolfer D, Kühn R, Unsicker K, Cestari V, Rossi-Arnaud C, Lipp H P, Bonhoeffer T, Klein R, ;1999;Neuron;24;401-14; 10571233

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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