B6.FVB-Tg(Htr1a-icre)1Fto/Orl

Status	Available to order
EMMA ID	EM:02129
International strain name	B6.FVB-Tg(Htr1a-icre)1Fto/Orl
Alternative name	5HT1AiCrefto
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Htr1a-icre)1Fto,
Gene/Transgene symbol	Tg(Htr1a-icre)1Fto

Information from provider

Provider	François (francois.tronche@gmail.com) TRONCHE
Provider affiliation	CNRS UMR6548
Genetic information	Transgenic mouse line expressing Cre recombinase in 5-HT1A receptor-expressing neurons. The 5-HT1A receptor ORF was substituted for that of Cre recombinase in a BAC containing the 5-HT1A receptor gene. The BAC construct contains 42 kb of DNA sequences upstream the 5-HT1A gene and 136 kb downstream. The "humanized" cre gene (iCre) was used. The transgene makes use of the endogenous polyA signal. In adult transgenic brain, Cre expression perfectly matched the distribution of 5-HT1A receptor mRNA.
Phenotypic information	None known.
References	5-HT1A-iCre, a new transgenic mouse line for genetic analyses of the serotonergic pathway.;Sahly Iman, Fabre Véronique, Vyas Sheela, Milet Aude, Rouzeau Jean-Denis, Hamon Michel, Lazar Monique, Tronche François, ;2007;Molecular and cellular neurosciences;36;27-35; 17656109

Information from EMMA

Archiving centre	Institut de Transgenose, INTRAGENE, Orléans, France

Literature references

5-HT1A-iCre, a new transgenic mouse line for genetic analyses of the serotonergic pathway.;Sahly Iman, Fabre Véronique, Vyas Sheela, Milet Aude, Rouzeau Jean-Denis, Hamon Michel, Lazar Monique, Tronche François, ;2007;Molecular and cellular neurosciences;36;27-35; 17656109

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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