B6;SJL-Tg(Tek-cre)1Ywa/Cnbc

Status

Available to order

EMMA IDEM:04325
International strain nameB6;SJL-Tg(Tek-cre)1Ywa/Cnbc
Alternative nameTie 2 Cre
Strain typeTransgenic Strains
Allele/Transgene symbolTg(Tek-cre)1Ywa
Gene/Transgene symbolTg(Tek-cre)1Ywa

Information from provider

ProviderMasashi Yanagisawa
Provider affiliationPsychiatry, University of Texas Southwestern Medical Center
Additional ownerStrain provided by University of Texas Southwestern Medical Center, Dallas TX, U.S.A.
Genetic informationIn Tie2Cre mice, Cre recombinase expression is tightly regulated under the control of endothelial specific Tie2 promoter and enhancer. The specific expression of Cre recombinase in endothelial cells is verified by crossing Tie2Cre mice with loxP-based reporter mice.
Phenotypic informationIn Tie2Cre mice, Cre recombinase expression is tightly regulated under the control of endothelial specific Tie2 promoter and enhancer. The specific expression of Cre recombinase in endothelial cells is verified by crossing Tie2Cre mice with loxP-based reporter mice.
Breeding historyBackcrossed to C57BL/6 an unknown number of times.
References
  • Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.;Kisanuki Y Y, Hammer R E, Miyazaki J, Williams S C, Richardson J A, Yanagisawa M, ;2001;Developmental biology;230;230-42; 11161575
  • Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice.;Schlaeger T M, Bartunkova S, Lawitts J A, Teichmann G, Risau W, Deutsch U, Sato T N, ;1997;Proceedings of the National Academy of Sciences of the United States of America;94;3058-63; 9096345
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous C57BL/6J, wild-type C57BL/6J
Stage of embryos2-cell

Literature references

  • Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.;Kisanuki Y Y, Hammer R E, Miyazaki J, Williams S C, Richardson J A, Yanagisawa M, ;2001;Developmental biology;230;230-42; 11161575
  • Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice.;Schlaeger T M, Bartunkova S, Lawitts J A, Teichmann G, Risau W, Deutsch U, Sato T N, ;1997;Proceedings of the National Academy of Sciences of the United States of America;94;3058-63; 9096345

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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