B6.Cg-Tg(dlx5a-cre)1Mekk/Cnrm
| Status | Available to order |
| EMMA ID | EM:04892 |
| International strain name | B6.Cg-Tg(dlx5a-cre)1Mekk/Cnrm |
| Alternative name | Dlx5/6-cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(dlx5a-cre)1Mekk, |
| Gene/Transgene symbol | Tg(dlx5a-cre)1Mekk |
Information from provider
| Provider | Marc Ekker |
| Provider affiliation | Ottawa Hospital Research Institute |
| Genetic information | A Cre gene was placed under the control of the I56i and I56ii enhancer elements of zebrafish dlx5a and a 3.5kb genomic DNA fragment flanking the 5'-region of the zebrafish dlx6a open reading frame and containing the 5'-UTR. |
| Phenotypic information | No abnormal phenotype detected. |
| Breeding history | The line was backcrossed in C57BL/6 for 14 generations and it is currently maintained by siblings breedings. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- The endocannabinoid system controls key epileptogenic circuits in the hippocampus.;Monory Krisztina, Massa Federico, Egertová Michaela, Eder Matthias, Blaudzun Heike, Westenbroek Ruth, Kelsch Wolfgang, Jacob Wolfgang, Marsch Rudolf, Ekker Marc, Long Jason, Rubenstein John L, Goebbels Sandra, Nave Klaus-Armin, During Matthew, Klugmann Matthias, Wölfel Barbara, Dodt Hans-Ulrich, Zieglgänsberger Walter, Wotjak Carsten T, Mackie Ken, Elphick Maurice R, Marsicano Giovanni, Lutz Beat, ;2006;Neuron;51;455-66; 16908411