B6.129P2-Creb1^tm4Gsc/Cnrm

Status	Available to order
EMMA ID	EM:00571
International strain name	B6.129P2-Creb1^tm4Gsc/Cnrm
Alternative name	CREB Ser142
Strain type	Targeted Mutant Strains : Knock-in
Allele/Transgene symbol	Creb1^tm4Gsc,
Gene/Transgene symbol	Creb1

Information from provider

Provider	Günther Schütz
Provider affiliation	Molecular Biology of the Cell I, German Cancer Research Center
Genetic information	Replacement of Creb1 Ser142 by Ala by homologous recombination.
Phenotypic information	Phase shift of the circadian clock.
References	Phosphorylation of CREB Ser142 regulates light-induced phase shifts of the circadian clock.;Gau Daniel, Lemberger Thomas, von Gall Charlotte, Kretz Oliver, Le Minh Nguyet, Gass Peter, Schmid Wolfgang, Schibler Ueli, Korf Horst W, Schütz Günther, ;2002;Neuron;34;245-53; 11970866

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Disease and phenotype information

MGI phenotypes (allele matching)

abnormal circadian behavior phase / MGI

Literature references

Phosphorylation of CREB Ser142 regulates light-induced phase shifts of the circadian clock.;Gau Daniel, Lemberger Thomas, von Gall Charlotte, Kretz Oliver, Le Minh Nguyet, Gass Peter, Schmid Wolfgang, Schibler Ueli, Korf Horst W, Schütz Günther, ;2002;Neuron;34;245-53; 11970866

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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B6.129P2-Creb1tm4Gsc/Cnrm