B6;129-Flrt2tm1c(EUCOMM)Wtsi/RobH
| Status | Available to order |
| EMMA ID | EM:08315 |
| International strain name | B6;129-Flrt2tm1c(EUCOMM)Wtsi/RobH |
| Alternative name | Flrt2 tm1c (EUCOMM) wtsi |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Flrt2tm1c(EUCOMM)Wtsi, |
| Gene/Transgene symbol | Flrt2 |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Genetic information | Floxed conditional allele for Flrt2 derived from the Flrt2 EUCOMM knock-out first mutation vector (EUCOMM ID:69623). Exposure of vector to flp recombinase excised the L1L2_Bact-P cassette (containing a LacZ sequence and neomycin under the control of human beta-actin promoter SV40) generating an allele with the Flrt2 coding exon flanked by loxP sites. |
| Phenotypic information | Homozygous:Homozygous floxed mice have no phenotype.Heterozygous:Heterozygous floxed mice have no phenotype. |
| Breeding history | Mice with the original Flrt2 EUCOMM knock-out first mutation vector were crossed with mice with flp recombinase. This generated mice heterozygous for the Flrt2 conditional allele. Heterozygous mice for the Flrt2 conditional allele were intercrossed to generate mice homozygous for the Flrt2 conditional allele. The strain has since been maintained as a homozygous line. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |