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PHENOMIN-ICS NR Collection
(72 EMMA strains found)


Nuclear receptors and co-regulators orchestrate diverse aspects of biological functions and inappropriate expression of these factors often associates with human diseases. 72 nuclear receptor family knock-out and conditional mouse lines generated by PHENOMIN-ICS are now available for worldwide distribution through EMMA.


EMMA ID Strain name Gene symbol Disease count
EM:12958B6J.129S2-Nr2c2tm1.1Ics/IcsNr2c2

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EM:12957B6J.129S2-Rxrgtm1.1Ics/IcsRxrg

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EM:12951B6J.129S2-Hnf4atm1.1Ics/IcsHnf4a4

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EM:12959B6J.129S2-Nr2c2tm1.2Ics/IcsNr2c2

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EM:12955B6J.129S2-Rxrgtm1.2Ics/IcsRxrg

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EM:12954B6J.129S2-Hnf4gtm1.2Ics/IcsHnf4g

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EM:12953B6J.129S2-Hnf4gtm1.1Ics/IcsHnf4g

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EM:12950B6J;129S2-Nr1i3tm1.2Ics/IcsNr1i3

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EM:12969B6J.129S2-Esrratm1.1Ics/IcsEsrra

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EM:12952B6J.129S2-Hnf4atm1.2Ics/IcsHnf4a4

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EM:12968B6J.129S2-Nr2f6tm1.2Ics/IcsNr2f6

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EM:12967B6J.129S2-Nr2f6tm1.1Ics/IcsNr2f6

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EM:12966B6J;129S2-Nr2f2tm1.2Ics/IcsNr2f2

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EM:12960B6J.129S2-Nr2e1tm1.1Ics/IcsNr2e1

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EM:12962B6J.129S2-Nr2e3tm1.1Ics/IcsNr2e32

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EM:12961B6J.129S2-Nr2e1tm1.2Ics/IcsNr2e1

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EM:12965B6J;129S2-Nr2f2tm1.1Ics/IcsNr2f2

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EM:12934B6J.129S2-Roratm1.1Ics/IcsRora

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EM:12933B6J.129S2-Nr1d2tm1.2Ics/IcsNr1d2

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EM:12939B6J.129S2-Rorctm1.2Ics/IcsRorc1

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EM:12938B6J.129S2-Rorctm1.1Ics/IcsRorc1

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EM:12935B6J;129S2-Roratm1.2Ics/IcsRora

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EM:12963B6J.129S2-Nr2e3tm1.2Ics/IcsNr2e32

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EM:12937B6J.129S2-Rorbtm1.2Ics/IcsRorb

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EM:12936B6J.129S2-Rorbtm1.1Ics/IcsRorb

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EM:12930B6J.129S2-Pparatm1.1Ics/IcsPpara

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EM:12947B6J.129S2-Nr1i2tm1.1Ics/IcsNr1i2

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EM:12932B6J.129S2-Nr1d2tm1.1Ics/IcsNr1d2

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EM:12946B6J.129S2-Nr1i2tm1.2Ics/IcsNr1i2

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EM:12944B6J.129S2-Nr1h4tm1.2Ics/IcsNr1h41

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EM:12931B6J.129S2-Pparatm1.2Ics/IcsPpara

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EM:12945B6J.129S2-Nr1h4tm1.1Ics/IcsNr1h41

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EM:12949B6J.129S2-Nr1i3tm1.1Ics/IcsNr1i3

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EM:12941B6J.129S2-Nr1h3tm1.2Ics/IcsNr1h3

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EM:12940B6J.129S2-Nr1h3tm1.1Ics/IcsNr1h3

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EM:12942B6J.129S2-Nr1h2tm1.1Ics/IcsNr1h2

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EM:12943B6J.129S2-Nr1h2tm1.2Ics/IcsNr1h2

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EM:12925B6J.129S2-Ncoa6tm1.2Ics/IcsNcoa6

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EM:12924B6J.129S2-Ncoa6tm1.1Ics/IcsNcoa6

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EM:12929B6J;129S2-Thrbtm1.2Ics/IcsThrb1

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EM:12928B6J;129S2-Thrbtm1.1Ics/IcsThrb1

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EM:12926B6J.129S2-Nr0b2tm1.1Ics/IcsNr0b2

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EM:12923B6J.129S2-Cops2tm1.2Ics/IcsCops2

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EM:12922B6J.129S2-Cops2tm1.1Ics/IcsCops2

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EM:12927B6J.129S2-Nr0b2tm1.2Ics/IcsNr0b2

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EM:12990B6J.129S2-Med1tm1.1Ics/IcsMed1

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EM:12999B6J.129S2-Ncor2tm1.1Ics/IcsNcor2

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EM:12997B6J.129S2-Ncor1tm1.1Ics/IcsNcor1

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EM:12992B6J;B6NTac-Ppargc1btm1.2Ics/IcsPpargc1b

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EM:12993B6J;B6NTac-Ppargc1btm1.1Ics/IcsPpargc1b

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EM:12991B6J.129S2-Med1tm1.2Ics/IcsMed1

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EM:12994B6J.129S2-Phb2tm1.1Ics/IcsPhb2

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EM:12998B6J.129S2-Ncor1tm1.2Ics/IcsNcor1

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EM:12995B6J.129S2-Phb2tm1.2Ics/IcsPhb2

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EM:12977B6J.129S2-Nr3c1tm1.2Ics/IcsNr3c11

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EM:12979B6.129S2-Nr3c2tm1.1Ics/IcsNr3c21

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EM:12978B6J.129S2-Nr3c2tm1.2Ics/IcsNr3c21

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EM:12971B6J.129S2-Esrrbtm1.1Ics/IcsEsrrb1

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EM:12970B6J.129S2-Esrratm1.2Ics/IcsEsrra

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EM:12976B6J.129S2-Nr3c1tm1.1Ics/IcsNr3c11

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EM:12975B6J.129S2-Esrrgtm1.2Ics/IcsEsrrg

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EM:12989B6J.129S2-Ncoa3tm1.2Ics/IcsNcoa3

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EM:12974B6J.129S2-Esrrgtm1.1Ics/IcsEsrrg

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EM:12973B6J.129S2-Esrrbtm1.2Ics/IcsEsrrb1

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EM:12983B6J.129S2-Nr5a1tm1.1Ics/IcsNr5a16

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EM:12982B6J.129S2-Pgrtm1.2Ics/IcsPgr

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EM:12987B6J.129S2-Ncoa3tm1.1Ics/IcsNcoa3

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EM:12985B6J.129S2-Nr6a1tm1.2Ics/IcsNr6a1

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EM:12986B6J;129S2-Nr6a1tm1.1Ics/IcsNr6a1

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EM:12984B6J.129S2-Nr5a1tm1.2Ics/IcsNr5a16

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EM:12981B6J;129S2-Pgrtm1.1Ics/IcsPgr

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EM:13000B6J.129S2-Ncor2tm1.2Ics/IcsNcor2

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Browse curated disease models

  • Nervous system

  • Selected strain collections

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