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A new publication of INFRAFRONTIER in Mammalian Genome is available on line now. Get an overview of the latest INFRAFRONTIER advancements, including services, resources, and technical developments.
New research identified an endogenous factor influencing amyloid pathology in Alzheimer’s disease using the APPPS1-21 mouse model. The study opens doors to novel polymorphism-based interventions.
Mouse models are relevant to study the functionality of genes involved in human diseases; however, translation of phenotypes can be challenging. This paper identified 153 genes associated with heart disease in humans, 151 with a one-to-one mouse ortholog.
